DOLUTEGRAVIR 50 mg + EMTRICITABINE 200 mg + TENOFOVIR ALAFENAMIDE 25 mg (Spegra) x 30 Tablets

Uses of Dolutegravir 50 mg + Emtricitabine 200 mg + Tenofovir Alafenamide 25 mg

• Treats HIV-1 infection
• Helps reduce the HIV viral load
• Helps increase or maintain CD4 cell counts
• Supports immune-system function
• May be used as a complete once-daily antiretroviral therapy regimen

Benefits

• Effectively suppresses HIV replication when taken as prescribed
• Supports improved immune-system function
• Helps maintain long-term viral suppression
• Reduces the risk of HIV-related infections and complications
• Provides convenient once-daily treatment in a single tablet

How Does Dolutegravir 50 mg + Emtricitabine 200 mg + Tenofovir Alafenamide 25 mg Work?

This combination contains dolutegravir, an integrase strand transfer inhibitor, and emtricitabine and tenofovir alafenamide, which are nucleoside and nucleotide reverse transcriptase inhibitors. Dolutegravir blocks the HIV integrase enzyme, while emtricitabine and tenofovir alafenamide prevent the virus from copying its genetic material. Together, these medicines stop HIV from multiplying, reduce the viral load, and help protect the immune system.

Side Effects

• Headache
• Nausea
• Diarrhoea
• Fatigue
• Insomnia
• Dizziness
• Skin rash
• Weight gain
• Elevated liver enzyme levels
• Changes in kidney function

Precautions

• Take the medicine exactly as prescribed by your healthcare provider.
• Inform your doctor if you have kidney disease, liver disease, or a current or previous hepatitis B infection.
• Regular monitoring of kidney function, liver function, CD4 count, and HIV viral load may be required.
• Tell your healthcare provider about all medicines, vitamins, antacids, and supplements you are taking to help prevent interactions.
• Do not stop treatment without medical advice, especially if you have hepatitis B infection.
• Use during pregnancy or breastfeeding only under the guidance of your healthcare provider.
• Continue following recommended measures to reduce the risk of transmitting HIV to others.