DASATINIB 50MG in India, The generic version of SPRYCEL, DASAKAST 50 mg, manufactured by APRAZER, is an oral medication prescribed for patients with blood cancer. SPRYCEL, also known as DASATINIB 50 mg in India, is effective for both pediatric and adult patients. Belonging to the class of kinase inhibitors, DASATINIB 50 mg is utilized in the treatment of blood cancer.
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DASAKAST 50Mg TABLETS MEDICINE DETAILS:
Product Name: Dasakast 50
Salt Name: Dasatinib 50mg
Manufactured By: Aprazer
Patent: Sprycel
Strength: 50mg
How DASATINIB Works
DASATINIB functions as an anti-cancer medication by inhibiting specific proteins (such as BCR-ABL, SRC kinase, etc.) in the body that are responsible for initiating cancer development. Consequently, it hinders the abnormal growth and proliferation of cancer cells within the body.
Common sides of DASATINIB 50 mg
- increased infections
- nausea, vomiting
- diarrhea, stomach pain, bloating, constipation, heartburn
- lack of appetite, changes in taste
- mouth ulcers, hair loss
- weight loss or weight gain
- headache, tiredness, weakness
- dizziness
- skin rash, itching, dry skin, acne
- increased bleeding tendency
- joint pain, muscle pain or spasms
- increased sweating, flushing
- blurred vision, dry eyes
- depression, sleeplessness
- oedema (swelling of body parts)
When to consult your doctor
Consult your doctor if you experience
- chest pain, cough, breathing difficulties and fainting (signs of fluid retention in lungs)
- unusual bleeding or bruising with fever, tiredness and confusion (signs of blood vessel damage)
- bloody stools/urine/vomit or black tarry stools
- blistering or peeling of skin and mucous membranes with fever and sore throat, mouth ulcers
Health tips of DASATINIB
1) Ensure sufficient hydration by drinking ample water throughout the day. Proper hydration is crucial for overall health and can aid in mitigating specific side effects, such as diarrhea or nausea, that may be linked to DASATINIB.
2) To reduce the potential for stomach upset or other gastrointestinal problems, consume this medication with food.
3) Steer clear of grapefruit and grapefruit juice, as their interaction with this medication could impact its effectiveness. It is advised to refrain from consuming grapefruit products while on this medication.
4) Ensure good hand hygiene by regularly washing your hands with soap and water, particularly before meals and after using the restroom. This practice is essential for minimizing the risk of infections, especially since this medicine may temporarily compromise the immune system.
5) Refrain from using antacids or any stomach medications simultaneously with DASATINIB maintain a time interval of at least 2 hours between the two treatments.
6) Due to the potential for causing congenital abnormalities, the use of DASATINIB is not advisable for pregnant or breastfeeding women.
7) Both male and female individuals undergoing DASATINIB therapy should employ an appropriate contraceptive method to prevent pregnancy.
Uses of DASATINIB 50mg in India
Utilized in the treatment of specific cancer types (chronic myeloid leukemia-CML, acute lymphoblastic leukemia-ALL), this medication functions by decelerating or halting the proliferation of cancer cells.
How to use DASATINIB Tablet
1) Before commencing DASATINIB 50mg in India with each refill, it is advisable to read the Patient Information Leaflet provided by your pharmacist. If you have any queries, consult your doctor or pharmacist.
2) Follow your doctor’s instructions and take this medication orally, with or without food, typically once daily. Ingest the tablets whole, and do not crush, chew, or break them.
3) Your dosage is determined by factors such as your medical condition, response to treatment, laboratory test results, and concurrent medications. For children, the dosage is also weight-dependent. It is crucial to inform your doctor and pharmacist about all the products you use, including prescription drugs, nonprescription drugs, and herbal products.
4) Avoid increasing your dosage or using this medication more frequently or for a longer duration than prescribed. Doing so will not expedite the improvement of your condition and may heighten the risk of experiencing serious side effects.
5) Refrain from using antacids (such as aluminum/magnesium hydroxide, calcium carbonate) within a 2-hour window before or after taking this medication, as they can impede the complete absorption of the drug by your body.
6) Refrain from consuming grapefruit or grapefruit juice while taking this medication unless your doctor or pharmacist has indicated that it is safe to do so. Grapefruit can elevate the risk of experiencing side effects with this medicine. Consult your doctor or pharmacist for additional information.
7) Pregnant women or those planning to become pregnant should avoid handling this medication or inhaling dust from the tablets, as the drug can be absorbed through the skin and lungs and may pose a risk to an unborn baby.
Side effects of DASATINIB
1) Should you encounter persistent or worsening symptoms such as diarrhea, nausea/vomiting, muscle/joint pain, or headache, it is important to promptly notify your doctor or pharmacist.
2) Individuals taking this medication may experience significant side effects. Nonetheless, your doctor has prescribed this drug based on the assessment that the benefits outweigh the potential risks. Diligent monitoring by your doctor can help reduce the likelihood of adverse effects.
3) If you experience any serious side effects, promptly inform your doctor. These may include a dry cough, swelling or pain in the hands, ankles, or feet, sudden or unexplained weight gain, shortness of breath, and signs of liver disease such as persistent nausea or vomiting, loss of appetite, stomach or abdominal pain, yellowing of eyes or skin, and dark urine.
4) Seek immediate medical assistance if you experience any highly serious side effects, such as vomiting resembling coffee grounds, black or bloody stools, severe dizziness, fainting, a fast/slow/irregular heartbeat, chest pain, confusion, or weakness on one side of the body.
5) Occasionally, DASATINIB can result in side effects attributed to the swift breakdown of cancer cells (tumor lysis syndrome). To mitigate this risk, your doctor may prescribe an additional medication and advise you to increase fluid intake. Notify your doctor promptly if you experience symptoms such as low back/side pain (flank pain), indications of kidney issues (such as painful urination, pink/bloody urine, alterations in urine volume), or muscle spasms/weakness.
6) This medication reduces bone marrow function, which can result in a decreased count of blood cells, including red cells, white cells, and platelets. This may lead to conditions such as anemia, a weakened ability to combat infections, or susceptibility to easy bruising and bleeding. Inform your doctor promptly if you experience any of the following symptoms: unusual fatigue ,pale skin, signs of persistent infection (like a sore throat that doesn’t improve, fever, chills), or easy bruising/bleeding.
7) While an extremely severe allergic reaction to this medication is uncommon, seek immediate medical assistance if you observe any indications of a serious allergic reaction, such as a rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing.
Precautions of DASATINIB 50mg in INDIA
1) Prior to initiating DASATINIB 50mg in India, inform your healthcare provider or pharmacist about any allergies you may have, including allergies to this medication or other substances. This product might contain inactive components, such as lactose, that could trigger allergic reactions or other complications. Consult your pharmacist for additional information.
2) Prior to starting this medication, inform your doctor or pharmacist about your medical history, particularly if you have a history of bleeding problems, current or recent infections, heart issues (such as irregular heartbeat), or liver problems (such as hepatitis B).
3) DASATINIB has the potential to induce a condition impacting the rhythm of the heart (QT prolongation). In rare instances, QT prolongation may lead to serious (occasionally fatal) instances of rapid or irregular heartbeat, accompanied by other symptoms like severe dizziness and fainting, necessitating immediate medical attention.
4) Inform your healthcare provider if you are pregnant or intend to conceive, as the use of DASATINIB is not advisable during pregnancy due to potential harm to the unborn baby. Before commencing this medication, your doctor should conduct a pregnancy test. Both men and women using this medication should inquire about dependable methods of contraception throughout the treatment period and for 30 days after the final dose. In the event of pregnancy, promptly consult your doctor to discuss the medication’s risks and benefits.
5) The passage of this drug into breast milk is uncertain. Due to the potential risk to the infant, it is advised to refrain from breastfeeding while using this medication and for a period of two weeks after the final dose. Before breastfeeding, seek guidance from your doctor.
Overdose:
1) In the event of an overdose, if an individual experiences severe symptoms such as loss of consciousness or difficulty breathing, seek medical attention immediately.
2) Avoid distributing this medication to anyone else.
3) Undergo regular laboratory and medical tests, including assessments such as bone growth and development in children, complete blood count, and liver function, while on this medication. Ensure attendance at all scheduled medical and lab appointments. For additional information, consult with your doctor.
4) If you forget to take a dose, omit the missed dose and resume your regular dosing schedule. Avoid doubling the dose to make up for the missed one.
5) Keep this medication at room temperature, shielded from light and moisture. Refrain from storing it in the bathroom. Ensure that all medications are kept out of reach of children and pets.